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Critically Compare Adenovirus And Herpes virus As Vectors And their Suitability For Use In Cancer Gene Therapy

Written By Albert Barkley on Friday, 19 October 2018 | 20:56

Adenoviruses are fatal kinds of viruses. These viruses have a lot of adverse effects on a human. These kinds of viruses can infect the membranes of organs of a human. In these organs, there come eyes, urinary tract, and the nervous system etc. The herpes viruses are also known as HPV. These kinds of viruses can become a cause of herpes. These kinds of herpes can appear in any part of the body but mainly they appear in the mouth. If you don’t have enough idea about these viruses and their suitability for cancer gene therapy, then you can get help from academic writing services.

Use of adenovirus as a vector in cancer gene therapy

Nowadays, gene therapy has become of the most important methods in order to treat different diseases with the help of genes. In a similar way, adenoviruses are also used in cancer gene therapy. The use of adenovirus as a vector in cancer gene therapy is explained below;

1) Suicide gene therapy is known as the first use of adenovirus in cancer gene therapy. Suicide gene therapy is known as a fascinating concept in the field of gene therapy for the treatment of different diseases. This kind of gene therapy ensures the delivery of tumour cells to the enzymes.

2) Secondly, there comes gene-based immunotherapy. It is a fact that almost all the patients of cancer develop the humoral and cellular immunes. This kind of essential gene therapy is essential for cancer patients to get rid of these kinds of immunes.

3) This kind of virus can also be used in gene replacement with the help of standard gene therapy techniques. For this reason, p53 cells are provided to the cancer patients. The p53 has enough ability to increase the radiation sensitivity of these cells.

4) These viruses are also helpful for the cure of the cancer patients with the help of the replication-competent treatment. With the help of this kind of technique, one can easily enhance the transaction and expression rate of cancer treatment.

5) Another important method to cure cancer patients with the help of adenoviruses is to adopt a technique of clinical trials of gene therapy.

6) There are also some cancer patients that are cured with the help of adenoviruses by adopting a technique of overview of trials by phase.

Use of herpes virus as a vector in cancer gene therapy

We can also use the herpes virus as a vector in cancer gene therapy. The use of HSV as a vector in cancer gene therapy is explained below;

1) It is an essential virus to show a broad range of the host cells and their receptors.

2) It is considered highly infectious in the treatment of cancer patients.

3) We can easily infect the non-dividing viruses with the help of this essential technique.

4) Its genes are nonessential for growth. Therefore, we can use these viruses for the treatment without any fear.

5) These HSV viruses can also act as recombinants. That’s why they can easily produce high tiers.
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